Why you should use Retinoath in your routine

Hydroxypinacolone Retinoate (HPR), also known under the trade name Granactive Retinoid, represents an innovative stride in the evolution of over-the-counter (OTC) retinoids. It belongs to the esteemed retinoid family, a group heralded for its pivotal role in skincare, particularly in anti-aging treatments. Within this family, retinoic acid, or tretinoin, has long been esteemed as the ultimate anti-aging solution, approved by the FDA for its efficacy. In comparison, HPR emerges as a new avenue for those seeking the benefits of retinoids without the associated drawbacks.

The formulation of HPR is distinct: it is produced with a 10% active ingredient concentration, accompanied by a 90% solvent component, dimethyl isosorbide. Hence, a product purporting to contain 2% Granactive Retinoid effectively includes 0.2% HPR and 1.8% dimethyl isosorbide.

HPR’s mechanism of action sets it apart from other members of the retinoid family. Unlike other retinoids that require conversion by the body’s metabolic systems into retinoic acid to become effective, HPR binds directly to the skin’s retinoid receptors. This direct action eliminates the need for conversion, positioning HPR as an immediately active ingredient capable of delivering significant skincare benefits without the intermediary steps required by other forms of retinoids.

Please see the chart:

Retinol —> Retinaldehyde —> Bioactive form of Vitamin A

Retinyl Palmitate —> Retinol —> Retinaldehyde —> Bioactive form of Vitamin A

Retinyl Acetate  —> Retinol  —> Retinaldehyde  —> Bioactive form of Vitamin A

Retinyl Propionate  —>  Retinol  —> Retinaldehyde  —> Bioactive form of Vitamin A

Tretinoin ( prescription Rx) = Bioactive form

Granactive retinoid ( HPR ) = Bioactive form ( NO CONVERSION NECESSARY)

Retinyl Lineolate =

—> Linoleic acid (Vitamin F) supports the skin barrier, making it less susceptible to side effects associated with retinol.

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Retinol –> Retinaldehyde = Bioactive form of Retinoid

One of the most compelling aspects of HPR is its efficacy coupled with a lower likelihood of irritation compared to traditional retinoids like retinol. Manufacturer-led studies suggest that HPR can achieve comparable results to retinoic acid in enhancing skin appearance and reducing signs of aging, such as lines and wrinkles, especially with regular application around delicate areas like the eyes. These findings highlight HPR’s potential as an effective, gentler alternative to its more irritating counterparts.